A224L

Alternative Names:

4CL, IAP, p27

Essential for Growth?:

Not required in Vero (ASFV-BA71V), Not required in primary macrophages (ASFV-Malawi Lil-20/1)

Essential for Virulence?:

No (ASFV-Malawi Lil-20/1)

Description:

Experimentally verified inhibitor of apoptosis protein caspase-3 and activates the transcription factor NF-κB. Late protein.