A238L

Alternative Names:

5EL, p28

Essential for Growth?:

Not required in Vero (ASFV-BA71V), Not required in primary macrophages (ASFV-Malawi Lil-20/1)

Essential for Virulence?:

No (ASFV-E70), No (ASFV-Malawi Lil-20/1)

Description:

Predicted IkB-like protein. Experimentally verified to inhibit NF-κB and the activity of the calcium/calmodulin-regulated phosphatase calcineurin. Early Protein.