DP71L

Alternative Names:

NL, NL-S

Essential for Growth?:

Not required in primary macrophages (ASFV-E70), Not required in primary macrophages (ASFV-Malawi Lil-20/1), Not required in primary macrophages (ASFV-Pretoriuskop/96/4)

Essential for Virulence?:

Yes (ASFV-E70), No (ASFV-Malawi Lil-20/1), No (ASFV-Pretoriuskop/96/4)

Description:

Encoded as a short form of (70-72 AA) or a long form (84 AA). Experimentally verified to bind and recruits protein phosphatase 1 catalytic subunit (PP1c) to dephosphorylate eukaryotic translation initiation factor 2 alpha.