EP402R

Alternative Names:

CD2v, CD2H, 8DR

Essential for Growth?:

Not required in Vero (ASFV-BA71V), Not required in primary macrophages (ASFV-G, 2010?), Not required in primary macrophages (ASFV-Malawi Lil-20/1)

Essential for Virulence?:

Yes (ASFV-BA71V), No (ASFV-G), Partially (ASFV-Malawi Lil-20/1)

Description:

Experimentally verified transmembrane protein, homologous to T-lymphocyte surface adhesion receptor CD2, that is responsible for adhesion to host red blood cells, immunomodulation and replication in ticks.