S273R

Alternative Names:

i6R

Essential for Growth?:

Yes (Determined by inducible promoter)

Essential for Virulence?:

unknown

Description:

Experimentally verified cysteine protease that cleaves structural proteins pp220 and pp62 . Additionally, S73R has been shown to target various host proteins leading to the inhibition of pyroptosis and cGAS-STING pathway mediated type I interferon (IFN) production.